TY - BOOK AU - Lean, Mike TI - Barasi’s Human nutrition : : a health perspective U1 - e-book (FST) PY - 2017/// CY - London PB - CRC Press N2 - Section I Foods, Nutrient Requirements and Nutrition Chapter 1 Introduction: What Is Nutrition?...................................................................................3 Aims..............................................................................................................................3 Definitions of Nutrition.................................................................................................3 Evidence-Based Nutrition.........................................................................................4 Why Is Nutrition Important?.........................................................................................4 What Do We Eat?..........................................................................................................6 How Is Information about People’s Diets Collected?....................................................7 Population and Household Information....................................................................7 Studying Nutrition.........................................................................................................8 Summary.......................................................................................................................8 Activity..........................................................................................................................9 Chapter 2 Nutrient Requirements and the Nutritionally Balanced Diet...................................... 11 Aims............................................................................................................................ 11 Diet Quality and the Nutritionally Balanced Diet...................................................... 11 Consumers and Health Claims............................................................................... 11 Nutritionally Balanced Diet: Which Foods to Choose?.............................................. 12 What Is the Difference between Meals and Snacks?............................................. 12 Nutritionally Balanced Diet: How Much to Eat?........................................................ 13 What Are the Features of a Nutritionally Balanced Diet?.......................................... 14 Eating More or Less of Particular Foods............................................................... 14 Eating More or Less of Particular Nutrients.......................................................... 14 Eating Specific Foods That Are Believed to Have ‘Health-Promoting’ Properties................................................................................................................ 15 What Nutrients Are Needed and in What Amounts?.................................................. 15 Nutritional Requirement......................................................................................... 16 Distribution of Nutritional Requirements in a Population.......................................... 17 From Requirements to Recommendations: Dietary Reference Values ...................... 18 Fats and Carbohydrates.......................................................................................... 19 Less-Studied Micronutrients..................................................................................20 Practical Applications.............................................................................................20 For Individuals...................................................................................................20 For Groups of Individuals.................................................................................. 21 For Dietary Planning......................................................................................... 21 Food Labelling................................................................................................... 21 vi Contents Dietary Planning.........................................................................................................22 Meal Planning Tools...............................................................................................22 Nutrition Information..................................................................................................26 The Question of Alcohol.............................................................................................26 Summary.....................................................................................................................27 Study Questions...........................................................................................................28 Activities.....................................................................................................................28 Bibliography and Further Reading..............................................................................29 Chapter 3 Macronutrients in Foods and Diets: Proteins, Carbohydrates and Fats...................... 31 Aims............................................................................................................................ 31 Proteins........................................................................................................................ 31 Amino Acids: The Building Blocks....................................................................... 32 Proteins in Food.....................................................................................................34 Protein Quality....................................................................................................... 35 Measuring Protein Quality................................................................................ 35 Protein Requirements.............................................................................................36 Carbohydrates.............................................................................................................38 What Are Carbohydrates?......................................................................................38 Monosaccharides............................................................................................... 39 Disaccharides.....................................................................................................40 Oligosaccharides................................................................................................ 41 Polysaccharides.................................................................................................. 41 How Much Carbohydrate Should We Have?.......................................................... 45 Fats.............................................................................................................................. 47 What Are Fats?....................................................................................................... 47 Triglycerides......................................................................................................48 Types of Fatty Acids..........................................................................................49 Essential Fatty Acids......................................................................................... 51 Conjugated Linoleic Acid.................................................................................. 52 Other Lipids....................................................................................................... 53 Fats in the Diet.......................................................................................................54 Sources of Fat in the Diet..................................................................................54 Sources of Essential Fatty Acids....................................................................... 55 Trends in Intakes of Fats.................................................................................... 55 How Much Fat Should We Have in the Diet?.........................................................56 Summary..................................................................................................................... 57 Proteins................................................................................................................... 57 Carbohydrates......................................................................................................... 57 Fats......................................................................................................................... 57 Study Questions........................................................................................................... 58 Activity........................................................................................................................ 58 Bibliography and Further Reading.............................................................................. 58 Chapter 4 Vitamins and Phytochemicals..................................................................................... 61 Aims............................................................................................................................ 61 Vitamins...................................................................................................................... 61 Fat-Soluble Vitamins.............................................................................................. 62 Vitamin A.......................................................................................................... 62 Contents vii Vitamin D..........................................................................................................64 Vitamin E...........................................................................................................65 Vitamin K..........................................................................................................66 Water-Soluble Vitamins.......................................................................................... 67 Thiamin (Vitamin B1)........................................................................................68 Riboflavin (Vitamin B2).....................................................................................68 Nicotinic Acid (Niacin, Vitamin B3).................................................................69 Vitamin B6......................................................................................................... 70 Folate................................................................................................................. 71 Vitamin B12........................................................................................................ 72 Pantothenic Acid (Vitamin B5).......................................................................... 73 Biotin (Vitamin B7)........................................................................................... 73 Vitamin C.......................................................................................................... 74 Phytochemicals........................................................................................................... 75 Phenolic Compounds, Including Flavonoids.......................................................... 76 Dietary Phytoestrogens.......................................................................................... 76 Phytosterols............................................................................................................77 Glucosinolates........................................................................................................ 78 Carotenoids............................................................................................................. 78 Use of Vitamin and Other Nutritional Supplements................................................... 79 Summary..................................................................................................................... 79 Study Questions...........................................................................................................80 Activity........................................................................................................................80 Bibliography and Further Reading..............................................................................80 Chapter 5 Minerals, Electrolytes and Fluid.................................................................................83 Aims............................................................................................................................83 Minerals......................................................................................................................83 Major Minerals.......................................................................................................85 Calcium..............................................................................................................85 Phosphorus.........................................................................................................86 Magnesium........................................................................................................86 Sulphur...............................................................................................................86 Microminerals or Trace Elements..........................................................................87 Iron.....................................................................................................................87 Zinc....................................................................................................................88 Copper...............................................................................................................88 Selenium............................................................................................................89 Iodine.................................................................................................................89 Chromium..........................................................................................................90 Fluoride..............................................................................................................90 Electrolytes.................................................................................................................. 91 Sodium and Chloride.............................................................................................. 91 Sodium and Chloride in Foods..........................................................................92 Dietary Reference Value....................................................................................92 Potassium................................................................................................................93 Dietary Reference Value....................................................................................93 Potassium in the Diet.........................................................................................93 Fluids: Keeping the Body Hydrated............................................................................93 What to Drink?.......................................................................................................93 viii Contents Water..................................................................................................................94 Soft Drinks........................................................................................................94 Fruit Juices.........................................................................................................94 Milk...................................................................................................................94 Tea and Coffee...................................................................................................94 How Much to Drink?..............................................................................................94 Water in Foods........................................................................................................94 Dehydration............................................................................................................95 Summary.....................................................................................................................96 Study Questions...........................................................................................................96 Activities.....................................................................................................................96 Bibliography and Further Reading..............................................................................97 Section II Nutrition through the Life Cycle Chapter 6 Nutrition during Pregnancy and Lactation ��������������������������������������������������������������� 101 Aims.......................................................................................................................... 101 Nutrition before Pregnancy....................................................................................... 102 Nutrition at the Time of Conception......................................................................... 103 Nutrition during Pregnancy....................................................................................... 104 What Are the Dietary Goals in Pregnancy?............................................................. 105 Diet in Pregnancy...................................................................................................... 106 Appetite................................................................................................................ 106 Energy.................................................................................................................. 106 Nutrients............................................................................................................... 106 Food Safety........................................................................................................... 107 Should Supplements Be Given?................................................................................. 108 Who Is Most at Risk in Pregnancy?.......................................................................... 109 Teenage Mothers.................................................................................................. 109 Low Income.......................................................................................................... 109 Underweight and Overweight Women................................................................. 110 Other Situations.................................................................................................... 110 Long-Term Consequences of Intrauterine Events..................................................... 110 Higher Blood Pressure.......................................................................................... 111 Insulin Resistance and Diabetes Mellitus............................................................ 112 Cholesterol Metabolism and Blood Clotting........................................................ 112 Other Conditions.................................................................................................. 113 Nursing or Lactating Mother..................................................................................... 115 Process of Lactation.................................................................................................. 115 Milk Production or Lactogenesis......................................................................... 115 Milk Ejection or Let Down.................................................................................. 115 Diet in Lactation........................................................................................................ 115 Energy.................................................................................................................. 116 Protein.................................................................................................................. 118 General Considerations............................................................................................. 118 Decision to Breastfeed.............................................................................................. 118 Summary................................................................................................................... 119 Contents ix Study Questions......................................................................................................... 119 Activities................................................................................................................... 119 Bibliography and Further Reading............................................................................ 120 Chapter 7 Nutrition during Infancy, Childhood and Adolescence............................................ 123 Aims.......................................................................................................................... 123 Infants........................................................................................................................ 123 Growth.................................................................................................................. 123 Nutrition and Development.................................................................................. 125 Development of the Digestive Tract................................................................ 125 Energy.............................................................................................................. 126 Protein.............................................................................................................. 127 Fats................................................................................................................... 127 Carbohydrates.................................................................................................. 127 Fluid................................................................................................................. 127 Minerals........................................................................................................... 128 Vitamins.......................................................................................................... 128 Meeting Nutritional Needs................................................................................... 128 Breastfeeding or Bottle-Feeding?............................................................................. 129 Formula Milk and Breast Milk Compared........................................................... 130 Proteins in Milk............................................................................................... 130 Carbohydrates in Milk..................................................................................... 131 Fats in Milk...................................................................................................... 131 Vitamins.......................................................................................................... 131 Minerals........................................................................................................... 131 Immunological Factors.................................................................................... 131 Other Factors................................................................................................... 132 Other Milks Available..................................................................................... 132 Future Health................................................................................................... 132 Weaning..................................................................................................................... 133 Why Should a Baby Be Weaned?......................................................................... 133 Child from 1 to 5 Years of Age................................................................................. 136 School-Age Children................................................................................................. 137 Influences on Nutritional Intakes......................................................................... 137 Autonomy........................................................................................................ 138 Growth............................................................................................................. 138 Activity............................................................................................................ 138 Societal Pressures............................................................................................ 139 Nutritional Needs................................................................................................. 139 What Do Children and Adolescents Eat?.................................................................. 141 Health-Related Aspects........................................................................................ 141 Dietary Patterns.................................................................................................... 141 Nutritional Intakes................................................................................................ 142 School Meals........................................................................................................ 144 Minimum Nutritional Standards..................................................................... 144 Alternatives to School Lunch.......................................................................... 146 Some Potential Nutritional Problems........................................................................ 147 Vegetarianism....................................................................................................... 147 Teenage Athletes.................................................................................................. 148 x Contents Pregnant Teenagers............................................................................................... 148 Dieting.................................................................................................................. 148 Smoking and Alcohol Use.................................................................................... 149 Summary................................................................................................................... 150 Study Questions......................................................................................................... 150 Activity...................................................................................................................... 150 Bibliography and Further Reading............................................................................ 150 Chapter 8 Nutrition during Adulthood and Ageing................................................................... 153 Aims.......................................................................................................................... 153 Adult Men.................................................................................................................. 154 Do Men Have Problems Achieving These Guidelines and Are They Appropriate?......................................................................................... 154 Adult Women............................................................................................................. 154 Vegetarians................................................................................................................ 155 Minority Ethnic Groups............................................................................................ 157 Low Income and Nutrition........................................................................................ 158 Characteristics of the Diet.................................................................................... 159 Nutritional Implications....................................................................................... 161 Practical Help....................................................................................................... 162 Older Adults.............................................................................................................. 163 Why Are Some Elderly Persons at Risk?............................................................. 164 Sensory System................................................................................................ 164 Gastrointestinal System................................................................................... 164 Kidney Function.............................................................................................. 165 Lean Tissue...................................................................................................... 165 Mobility........................................................................................................... 165 Immune System............................................................................................... 168 Brain and Nervous System.............................................................................. 168 Other Factors................................................................................................... 169 Factors Affecting Nutritional Status.................................................................... 169 Inadequate Intake............................................................................................ 169 Less Efficient Digestion and Absorption......................................................... 170 Altered Needs.................................................................................................. 170 What Is the Nutritional State of Older Adults?.................................................... 171 What Are the Nutritional Requirements for the Elderly?.................................... 173 Summary................................................................................................................... 175 Study Questions......................................................................................................... 175 Activities................................................................................................................... 176 Bibliography and Further Reading............................................................................ 176 Section III Digestion, Absorption and Nutrient Metabolism Chapter 9 Gut Structures, Functions and Control of Digestion................................................. 181 Aims.......................................................................................................................... 181 Basic Anatomy and Physiology................................................................................. 181 Contents xi Functions of the GI Tract.......................................................................................... 182 Digestion............................................................................................................... 183 Secretion............................................................................................................... 183 Motility................................................................................................................. 185 Absorption............................................................................................................ 186 Control of Eating and Digestive Functions............................................................... 186 Sensory Signals.................................................................................................... 188 Pre-Absorptive Information................................................................................. 188 Post-Absorptive Signals........................................................................................ 188 Metabolism........................................................................................................... 189 Integration by the Brain........................................................................................ 190 Summary................................................................................................................... 190 Study Questions......................................................................................................... 190 Activity...................................................................................................................... 191 Bibliography and Further Reading............................................................................ 191 Chapter 10 Digestion and Absorption of Nutrients..................................................................... 193 Aims.......................................................................................................................... 193 Digestion and Absorption of Macronutrients............................................................ 193 Proteins................................................................................................................. 193 Digestion of Proteins....................................................................................... 193 Absorption of the Products of Protein Digestion............................................. 193 Fats....................................................................................................................... 195 Digestion of Fats.............................................................................................. 195 Absorption of the Products of Fat Digestion................................................... 195 Carbohydrates....................................................................................................... 197 Digestion of Carbohydrates............................................................................. 197 Absorption of Carbohydrates........................................................................... 199 Digestion and Absorption of Vitamins..................................................................... 201 Vitamin A............................................................................................................. 201 Vitamin D.............................................................................................................202 Vitamin E.............................................................................................................202 Vitamin K.............................................................................................................202 Thiamin................................................................................................................203 Riboflavin.............................................................................................................203 Niacin...................................................................................................................203 Vitamin B6............................................................................................................203 Folate....................................................................................................................203 Vitamin B12...........................................................................................................203 Vitamin C.............................................................................................................204 Digestion and Absorption of Minerals, Trace Elements and Electrolytes................204 Calcium................................................................................................................204 Enhancing factors............................................................................................204 Inhibitory factors.............................................................................................205 Phosphorus...........................................................................................................206 Magnesium...........................................................................................................206 Iron.......................................................................................................................206 Control of absorption.......................................................................................207 Zinc.......................................................................................................................208 xii Contents Copper..................................................................................................................208 Selenium...............................................................................................................208 Iodine....................................................................................................................209 Fluoride................................................................................................................209 Sodium and Chloride............................................................................................209 Potassium..............................................................................................................209 Fluid Balances................................................................................................. 210 Digestion and Absorption of Phytochemicals........................................................... 212 Summary................................................................................................................... 213 Study Questions......................................................................................................... 214 Activity...................................................................................................................... 214 Bibliography and Further Reading............................................................................ 214 Chapter 11 Metabolism and Function of Macronutrients............................................................ 215 Aims.......................................................................................................................... 215 Proteins...................................................................................................................... 215 Amino Acid Metabolism........................................................................................... 215 Amino Acid Pool.................................................................................................. 216 Control of Protein Metabolism............................................................................. 218 Contribution of Protein to Body Composition................................................. 218 Formation of Enzymes.................................................................................... 219 Homeostasis..................................................................................................... 219 Hormones......................................................................................................... 219 Acid–Base Balance.......................................................................................... 219 Fluid Balance................................................................................................... 219 Immunity......................................................................................................... 219 Transport.......................................................................................................... 219 Blood Clotting.................................................................................................220 Other Functions...............................................................................................220 Fats............................................................................................................................220 Metabolic Roles....................................................................................................220 Meeting the Energy Needs: Fat Metabolism...................................................220 Fat Requires Specialized Proteins for Transport around the Body................. 221 Storage: The Adipose Tissue...........................................................................223 Adipose Tissue and Metabolic Regulation......................................................224 Fat Utilization..................................................................................................224 Functions of Fat in the Body...........................................................................225 Structure of Membranes..................................................................................226 Link with Glucose Metabolism: Insulin Resistance........................................226 Steroid Metabolism..........................................................................................226 Essential Fatty Acids.......................................................................................226 Carbohydrates...........................................................................................................228 Carbohydrates Metabolism...................................................................................229 Carbohydrate Storage...........................................................................................229 Glycogenesis....................................................................................................229 Lipogenesis......................................................................................................229 Mobilization of Carbohydrates.............................................................................229 Glycogenolysis/Glycolysis...............................................................................229 Gluconeogenesis..............................................................................................230 Contents xiii Metabolic Consequences of Sugar Intake....................................................... 231 Other Physiological Roles of Carbohydrates................................................... 231 Gut Health........................................................................................................ 231 Summary................................................................................................................... 233 Study Questions......................................................................................................... 233 Bibliography and Further Reading............................................................................ 233 Chapter 12 Metabolism and Function of Micronutrients............................................................. 235 Aims.......................................................................................................................... 235 Vitamins.................................................................................................................... 235 Vitamin A............................................................................................................. 235 Vision...............................................................................................................236 Cellular Differentiation.................................................................................... 237 Growth.............................................................................................................238 Antioxidant Role..............................................................................................238 Other Functions...............................................................................................238 Vitamin D.............................................................................................................238 Vitamin E............................................................................................................. 239 Vitamin C.............................................................................................................240 Vitamin K.............................................................................................................240 Thiamin (Vitamin B1)........................................................................................... 241 Riboflavin (Vitamin B2)....................................................................................... 241 Niacin (Vitamin B3).............................................................................................. 241 Pyridoxine (Vitamin B6)......................................................................................242 Folate (Vitamin B9)..............................................................................................242 Cobalamin (Vitamin B12)..................................................................................... 243 Pantothenic Acid (Vitamin B5)............................................................................. 243 Biotin (Vitamin B7)..............................................................................................244 Minerals....................................................................................................................244 Calcium................................................................................................................244 In Bones...........................................................................................................244 In Blood and Body Fluids................................................................................244 Why Does Plasma Calcium Need to Be Closely Regulated?..........................246 Phosphorus...........................................................................................................246 Magnesium...........................................................................................................246 Iron....................................................................................................................... 247 Losses of Iron.................................................................................................. 247 Stored Iron....................................................................................................... 247 Zinc.......................................................................................................................248 Copper..................................................................................................................248 Selenium...............................................................................................................249 Iodine....................................................................................................................249 Chromium.............................................................................................................250 Sodium, Chloride and Potassium.........................................................................250 Summary................................................................................................................... 251 Study Questions......................................................................................................... 251 Activities................................................................................................................... 252 Bibliography and Further Reading............................................................................ 252 xiv Contents Section IV Eating Behaviour and Nutritional Epidemiology Chapter 13 Habits and Influences on Eating Behaviours............................................................ 255 Aims.......................................................................................................................... 255 Reasons for Eating.................................................................................................... 255 Habit as an Influence on Eating Behaviour.......................................................... 255 Psychological Drivers for Eating..........................................................................256 Sensory Appeal....................................................................................................256 Social Influence.................................................................................................... 257 Food Habits............................................................................................................... 258 Acquisition of Food Habits................................................................................... 259 Changing Food Habits.......................................................................................... 259 Food Choices........................................................................................................260 Availability........................................................................................................... 261 Physical/Environmental Factors...................................................................... 261 Legislative Factors........................................................................................... 262 Affordability, Cost and Taxation..................................................................... 262 Accessibility.................................................................................................... 262 Acceptability........................................................................................................263 Cultural Factors...............................................................................................263 Physiological Factors.......................................................................................264 Social/Psychological Influences......................................................................265 Summary................................................................................................................... 267 Study Questions......................................................................................................... 267 Activities................................................................................................................... 267 Bibliography and Further Reading............................................................................268 Chapter 14 Diet and Coronary Heart Disease.............................................................................269 Aims..........................................................................................................................269 Changes in Rates of Cardiovascular Disease............................................................ 270 What Is Coronary Heart Disease?............................................................................. 270 Injury to the Coronary Arteries............................................................................ 271 Fibrous Plaque Formation.................................................................................... 271 Thrombosis and Heart Attack.............................................................................. 271 Studying Coronary Heart Disease............................................................................ 273 Origins of the Lipid Hypothesis........................................................................... 273 Cross-Community Comparisons..................................................................... 273 Prospective Studies.......................................................................................... 274 Intervention Studies......................................................................................... 274 Risk Factors............................................................................................................... 276 Genetic Predisposition..........................................................................................277 Age........................................................................................................................277 Social Conditions and Social Inequality..............................................................277 Birthweight........................................................................................................... 278 Geographical Location and Sunlight................................................................... 278 Disease.................................................................................................................. 279 Smoking................................................................................................................ 279 Contents xv High Blood Pressure.............................................................................................280 Raised Blood Lipids.............................................................................................280 Weight...................................................................................................................280 Physical Activity................................................................................................... 281 Psychosocial Factors............................................................................................. 281 Dietary Factors..................................................................................................... 281 Fats...................................................................................................................282 Total Energy....................................................................................................285 Salt...................................................................................................................285 Calcium............................................................................................................286 Alcohol............................................................................................................286 Fibre (Non-Starch Polysaccharides)................................................................286 Antioxidants.....................................................................................................287 Homocysteine and Folate.................................................................................289 Future Directions.......................................................................................................290 Summary...................................................................................................................290 Study Questions.........................................................................................................290 Bibliography and Further Reading............................................................................290 Chapter 15 Diet and Cancer.........................................................................................................293 Aims..........................................................................................................................293 What Is Cancer?........................................................................................................294 Studying the Relationship between Diet and Cancer................................................294 Ecological or Correlational Studies...................................................................... 295 Case–Control Studies........................................................................................... 295 Prospective Cohort Studies..................................................................................296 Meta-Analysis.......................................................................................................296 Environmental Causes of Cancer..............................................................................296 Role of Diet...........................................................................................................297 Possible Promoting Factors..................................................................................298 Total Energy Intake.........................................................................................298 Fat Intakes........................................................................................................298 Alcohol............................................................................................................299 Salt...................................................................................................................300 Meat and Fish..................................................................................................300 Other Promoters of Cancer.............................................................................. 301 Possible Protective Factors................................................................................... 301 Nonstarch Polysaccharides (Dietary Fibre).....................................................302 Fruit and Vegetables........................................................................................303 Antioxidant Nutrients......................................................................................303 Other Chemically Active Constituents............................................................304 Calcium............................................................................................................304 Prevention of Cancer.................................................................................................305 Summary...................................................................................................................308 Study Questions.........................................................................................................308 Activities...................................................................................................................308 Bibliography and Further Reading............................................................................309 xvi Contents Section V Dietary and Nutritional Assessment Chapter 16 Energy: Intake and Expenditure............................................................................... 313 Aims.......................................................................................................................... 313 Units of Measurement of Energy.............................................................................. 313 Energy Intake............................................................................................................ 314 Energy Content of Foods...................................................................................... 314 Bomb Calorimeter........................................................................................... 314 Proximate Principles........................................................................................ 315 Dietary Assessment.............................................................................................. 317 Contribution from Food Groups...................................................................... 317 Energy Output........................................................................................................... 318 Basal Metabolic Rate............................................................................................ 318 Influence of Body Weight................................................................................ 320 Influence of Gender......................................................................................... 320 Influence of Age.............................................................................................. 320 Influence of Disease Status.............................................................................. 320 Thermogenesis...................................................................................................... 321 Physical Activity................................................................................................... 321 Measurement of Energy Output........................................................................... 322 Direct Calorimetry..........................................................................................324 Indirect Methods..............................................................................................324 Calculation of Energy Expenditure........................................................................... 325 Calculation of 24-Hour Energy Expenditure: An Example................................. 326 Summary................................................................................................................... 327 Study Questions......................................................................................................... 327 Activities................................................................................................................... 327 Bibliography and Further Reading............................................................................ 329 Chapter 17 Energy Balance......................................................................................................... 331 Aims.......................................................................................................................... 331 Energy Balance......................................................................................................... 331 Influences on Energy Intake................................................................................. 332 Influences on Energy Output................................................................................ 332 Adaptations to Basal Metabolic Rate.............................................................. 332 Adaptations to Thermogenesis........................................................................ 333 Adaptations to Physical Activity..................................................................... 334 How Well Is Energy Balance Controlled?................................................................ 335 Control Mechanisms............................................................................................. 335 Energy Balance and Imbalance................................................................................. 337 Negative Energy Balance..................................................................................... 337 The Fasted State................................................................................................... 338 Starvation.............................................................................................................. 338 Positive Energy Balance....................................................................................... 339 Energy Balance and Body Composition...............................................................340 Summary................................................................................................................... 341 Study Questions......................................................................................................... 341 Bibliography and Further Reading............................................................................ 341 Contents xvii Chapter 18 Dietary and Nutritional Assessment......................................................................... 343 Aims.......................................................................................................................... 343 Nutritional Status...................................................................................................... 343 What We Eat: Diet Composition.......................................................................... 343 What We Are: Body Composition........................................................................ 343 What We (Can) Do: Function...............................................................................344 What We Pass On.................................................................................................344 What We Eat: Dietary Assessment...........................................................................344 The Weighed Inventory (or Weighed Dietary Record)........................................344 Food Diaries (or Estimated Dietary Records)...................................................... 345 Food Frequency Questionnaires (FFQs).............................................................. 345 The Diet Interview................................................................................................346 Practical Issues in Dietary Assessment Methods.................................................346 Misreporting....................................................................................................346 Measurement Errors, Bias and Precision......................................................... 347 Validity............................................................................................................ 347 What We Are: Body Composition.............................................................................348 Measuring Body Composition..................................................................................348 Body Mass Index..................................................................................................348 Skinfold and Skeletal Measurements................................................................... 350 Anthropometry..................................................................................................... 351 Underwater Weighing........................................................................................... 353 Other Indirect Methods........................................................................................ 353 Bioelectrical Impedance.................................................................................. 353 Ultrasound....................................................................................................... 353 Other Techniques............................................................................................. 354 What Are the Average Values for Body Composition?............................................. 354 What We Can Do: Functional Capacity.................................................................... 354 Biochemical Indicators.............................................................................................. 355 Clinical Indicators..................................................................................................... 355 What Can We Learn from Nutritional Assessment?................................................. 356 How Is Nutritional Status Information Used?........................................................... 357 Summary................................................................................................................... 357 Study Questions......................................................................................................... 358 Activity...................................................................................................................... 358 Bibliography and Further Reading............................................................................ 358 Section VI Applied Nutrition Chapter 19 Introduction to Public Health Nutrition and Health Promotion................................ 363 Aims.......................................................................................................................... 363 What Is the Basis of Health-Promoting Policies and What Is Proposed?.................366 Dietary Links.......................................................................................................366 Lifestyle and Social Factors.................................................................................366 Undernutrition, Malnutrition and the Double Burden of Disease in Developing Countries...........................................................................................369 From Goals to Guidelines....................................................................................369 xviii Contents What Is Health Promotion?....................................................................................... 371 Planning................................................................................................................ 372 Intervention........................................................................................................... 373 Evaluation............................................................................................................. 374 Health-Promotion Initiatives and the Individual....................................................... 375 Information and Education................................................................................... 375 Schools.................................................................................................................. 376 The NHS and Health Professionals...................................................................... 376 Media/Advertising................................................................................................ 376 The Food Chain.................................................................................................... 377 Constraints............................................................................................................ 377 A Targeted Policy................................................................................................. 377 Economics of Health Promotion............................................................................... 379 Summary...................................................................................................................380 Study Questions.........................................................................................................380 Activities................................................................................................................... 381 Bibliography and Further Reading............................................................................ 381 Chapter 20 Introduction to Obesity and Weight Management.................................................... 383 Aims.......................................................................................................................... 383 Obesity: What Are the Reasons?............................................................................... 383 Dietary Intake: Energy Consumption and Obesity.............................................. 385 Physical Activity................................................................................................... 388 Genetic Predisposition..........................................................................................388 Age and Gender.................................................................................................... 389 Socio-Economic status.............................................................................................. 389 Psychological Factors...........................................................................................390 Health Risks and Costs of Overweight and Obesity.................................................390 Treatment of Obesity/Overweight............................................................................. 392 Energy-Controlled Diets....................................................................................... 393 Pharmacological Agents....................................................................................... 394 Surgical Intervention (‘Bariatric Surgery’).......................................................... 395 Psychological and Behavioural Therapy.............................................................. 395 Physical Activity................................................................................................... 395 Unsafe Methods of Weight Loss.......................................................................... 396 Summary................................................................................................................... 396 Study Questions.........................................................................................................397 Activity......................................................................................................................397 Bibliography and Further Reading............................................................................397 Chapter 21 Introduction to Clinical Nutrition.............................................................................399 Aims..........................................................................................................................399 Negative Energy Balance..........................................................................................400 Weight Loss Due to Illness................................................................................... 401 Correcting Weight Loss........................................................................................ 401 Starvation and Refeeding.....................................................................................402 Malnutrition Screening and Diagnosis......................................................................403 Screening Tools....................................................................................................403 Nutritional Support: Enteral and Parenteral Feeding................................................405 Contents xix Clinical Micronutrient Deficiencies..........................................................................406 Adverse Reactions to Food........................................................................................406 Food Poisoning.....................................................................................................407 Food Aversion.......................................................................................................407 Food Intolerance...................................................................................................408 Why Do Some Individuals Develop Food Allergy? Atopy............................. 410 Diagnosis.............................................................................................................. 411 Effect of Infection on Nutritional Status.............................................................. 412 Effect of Nutritional Status on Immunity............................................................. 413 Nutrition Management and Cancer...................................................................... 414 Nutrition Management and Metabolic Disorders................................................. 414 Drug–Nutrient Interactions....................................................................................... 414 Effects of Diet on Drugs....................................................................................... 415 Dietary Factors Affecting Drug Metabolism.................................................. 415 Dietary Factors Affecting Drug Excretion...................................................... 415 Drug Effects on Food Intake........................................................................... 415 Gastro-Intestinal Function............................................................................... 415 Metabolic Effects of Drugs on Nutrients......................................................... 416 Influence of Disability on Nutrition.......................................................................... 416 Appetite................................................................................................................ 417 Ability to Obtain and Prepare Food..................................................................... 417 Ability to Ingest, Chew and Swallow Food.......................................................... 417 Impact on Digestion and Absorption.................................................................... 417 Impact on Metabolism.......................................................................................... 418 Nutritional Consequences..................................................................................... 418 Eating Disorders........................................................................................................ 418 Summary................................................................................................................... 419 Study Questions......................................................................................................... 419 Bibliography and Further Reading............................................................................ 419 Chapter 22 Introduction to Sport Nutrition.................................................................................. 421 Aims.......................................................................................................................... 421 Nutrition and the Athlete........................................................................................... 421 Energy Needs in Sport......................................................................................... 422 Energy as Adenosine Triphosphate (ATP)........................................................... 422 Energy from Fat and Carbohydrates.................................................................... 423 During Training............................................................................................... 425 After Exercise.................................................................................................. 425 Protein Needs....................................................................................................... 426 Dietary Supplements............................................................................................ 427 Vitamin and Mineral Supplements.................................................................. 427 Creatine............................................................................................................ 427 Fluid...................................................................................................................... 428 Sports Products..................................................................................................... 429 Summary................................................................................................................... 429 Study Questions......................................................................................................... 430 Activities................................................................................................................... 430 Bibliography and Further Reading............................................................................ 430 xx Contents Chapter 23 Improving Foods for Better Nutrition....................................................................... 431 Aims.......................................................................................................................... 431 Foods, Food Components and Health Claims........................................................... 432 Terminology......................................................................................................... 433 Smart Foods.............................................................................................................. 433 Foods with Novel Molecular Structures............................................................... 433 Meat Analogues.................................................................................................... 434 Foods Produced by Biotechnology....................................................................... 434 Functional Foods.................................................................................................. 435 Fortified Foods..................................................................................................... 435 Reduced Content of Nutrients......................................................................... 436 Foods Containing Phytochemicals.................................................................. 436 Foods with Added Components...................................................................... 436 Omega-Enriched Eggs..................................................................................... 437 Clinical Usage.................................................................................................. 437 Foods Containing Bacteria.............................................................................. 437 Food Reformulation.................................................................................................. 439 Nutrient Profiling...................................................................................................... 441 Organic Food.............................................................................................................442 Conclusions...............................................................................................................443 Summary...................................................................................................................443 Study Questions.........................................................................................................443 Activities...................................................................................................................444 Bibliography and Further Reading............................................................................444 Index...............................................................................................................................................447 ER -